Asish K Saha Selected Research

Malonyl Coenzyme A (Malonyl CoA)

3/2015	Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats.
5/2006	Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA.
3/2006	Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats.
2/2006	Metabolic syndrome: adenosine monophosphate-activated protein kinase and malonyl coenzyme A.
2/2005	AMPK, the metabolic syndrome and cancer.
2/2004	Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo.
1/2003	Insulin resistance in type 2 diabetes: association with truncal obesity, impaired fitness, and atypical malonyl coenzyme A regulation.
5/2002	Regulation of muscle malonyl-CoA levels in the nutritionally insulin-resistant desert gerbil, Psammomys obesus.

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Asish K Saha Research Topics

Disease

19	Insulin Resistance 01/2021 - 05/2002
10	Type 2 Diabetes Mellitus (MODY) 01/2017 - 10/2002
5	Obesity 03/2016 - 01/2003
3	Neoplasms (Cancer) 01/2019 - 02/2005
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2006 - 02/2005
2	Metabolic Diseases (Metabolic Disease) 01/2017 - 01/2014
2	Breast Neoplasms (Breast Cancer) 10/2015 - 07/2005
2	Anorexia 03/2015 - 05/2006
2	Hyperglycemia 05/2011 - 03/2006
2	Tuberous Sclerosis (Bourneville's Disease) 10/2010 - 02/2005
2	Prostatic Neoplasms (Prostate Cancer) 06/2010 - 08/2004
1	Inflammation (Inflammations) 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 01/2019
1	Septic Shock (Toxic Shock Syndrome) 01/2018
1	Weight Gain 03/2016
1	Fatty Liver 03/2016
1	Dyslipidemias (Dyslipidemia) 03/2016
1	Hyperphagia (Overeating) 03/2015
1	Hyperthyroidism 09/2010
1	Weight Loss (Weight Reduction) 09/2010
1	AIDS-Related Complex (ARC) 08/2010
1	Pancreatic Neoplasms (Pancreatic Cancer) 06/2010
1	Cardiovascular Diseases (Cardiovascular Disease) 04/2010
1	Coronary Disease (Coronary Heart Disease) 12/2006
1	Glucose Intolerance 02/2006
1	Atherosclerosis 05/2004
1	Hypertriglyceridemia 02/2004
1	Hypoxia (Hypoxemia) 07/2003
1	Body Weight (Weight, Body) 01/2003
1	Overweight 01/2003
1	Hypoglycemia (Reactive Hypoglycemia) 05/2002
1	Hyperinsulinism (Hyperinsulinemia) 05/2002

Drug/Important Bio-Agent (IBA)

12	AMP-Activated Protein KinasesIBA 01/2017 - 12/2002
11	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 05/2002
9	Insulin (Novolin)FDA Link 07/2013 - 05/2002
8	Fatty Acids (Saturated Fatty Acids)IBA 01/2018 - 05/2002
8	Malonyl Coenzyme A (Malonyl CoA)IBA 03/2015 - 05/2002
7	EnzymesIBA 01/2017 - 12/2002
4	Acetyl-CoA CarboxylaseIBA 01/2019 - 03/2006
4	AdiponectinIBA 07/2006 - 05/2004
3	LeptinIBA 03/2015 - 05/2004
3	Leucine (L-Leucine)FDA Link 01/2015 - 10/2010
3	Sirolimus (Rapamycin)FDA Link 07/2013 - 02/2005
3	AICA ribonucleotide (ZMP)IBA 10/2011 - 06/2010
3	Proteins (Proteins, Gene)FDA Link 10/2010 - 12/2002
3	ThiazolidinedionesIBA 07/2006 - 01/2005
2	Protein Kinases (Protein Kinase)IBA 01/2021 - 02/2006
2	Adenosine Monophosphate (AMP)IBA 01/2021 - 02/2006
2	Phosphotransferases (Kinase)IBA 01/2019 - 02/2005
2	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 07/2013 - 10/2011
2	Thioctic Acid (Lipoic Acid)IBA 10/2011 - 10/2010
2	GhrelinIBA 08/2010 - 10/2009
2	Interleukin-6 (Interleukin 6)IBA 12/2006 - 05/2004
2	Tamoxifen FDA LinkGeneric 05/2006 - 07/2005
2	Hormones (Hormone)IBA 02/2006 - 01/2005
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2021
1	PolyphenolsIBA 01/2021
1	Sorafenib (BAY 43-9006)FDA Link 01/2019
1	LipopolysaccharidesIBA 01/2018
1	Volatile Fatty AcidsIBA 01/2018
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2018
1	Alanine (L-Alanine)FDA Link 01/2018
1	pyruvate dehydrogenase kinase 4IBA 01/2018
1	Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA 01/2018
1	IsoenzymesIBA 03/2016
1	ND-630IBA 03/2016
1	PoisonsIBA 10/2015
1	Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA 03/2015
1	Appetite Depressants (Anorectics)IBA 03/2015
1	Branched-Chain Amino AcidsIBA 10/2011
1	MTOR InhibitorsIBA 10/2010
1	Thyroid HormonesIBA 09/2010
1	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 09/2010
1	Triiodothyronine (Liothyronine)FDA LinkGeneric 09/2010
1	Agouti-Related ProteinIBA 08/2010
1	NeuropeptidesIBA 08/2010
1	Neuropeptide YIBA 08/2010
1	AndrogensIBA 06/2010
1	1,25-dihydroxyvitamin D3-3-bromoacetateIBA 06/2010
1	3-Hydroxybutyric Acid (beta-Hydroxybutyric Acid)IBA 05/2009
1	Transcription Factors (Transcription Factor)IBA 05/2009
1	AdipokinesIBA 07/2006
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 05/2006
1	LipidsIBA 03/2006
1	Triglycerides (Triacylglycerol)IBA 03/2006
1	12- (4'- azido- 2'- nitrophenoxy)dodecanoyl- coenzyme AIBA 03/2006
1	Acyl Coenzyme A (Acyl CoA)IBA 03/2006
1	DiglyceridesIBA 03/2006
1	PPAR gammaIBA 02/2006
1	CholesterolIBA 07/2005
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2005
1	Metformin (Glucophage)FDA LinkGeneric 01/2005
1	Leptin ReceptorsIBA 05/2004
1	Pioglitazone (Actos)FDA Link 02/2004
1	Coenzyme A (CoA)IBA 01/2003
1	Nonesterified Fatty Acids (NEFA)IBA 01/2003
1	Complement System Proteins (Complement)IBA 12/2002
1	Citric Acid (Citrate)FDA LinkGeneric 05/2002
1	malic acid (malate)IBA 05/2002

Therapy/Procedure

2	Therapeutics 10/2015 - 04/2010